一、教育、工作经历：

2023年3与月-至今，东莞理工学院生命健康技术学院，讲师

2018年9月-2022年12月，华南理工大学医学院，博士

2015年9月-2018年6月，西南大学药学院，硕士

2011年9月-2015年6月，河南中医药大学药学院，学士

二、研究领域：

主要从事研究领域包括：探讨生物活性材料对突变p53、β淀粉样等致病蛋白调控的机制；从中药中分离的小分子以及蛋白大分子活性成分抗肿瘤机制研究；以斑马鱼为模式生物进行药物筛选、毒性发现以及安全性评价研究。

三、主要业绩：

主持中央高校基本科学业务专项项目一项，参与国家自然科学基金面上及重点等多项项目的研究；在国内外SCI期刊发表学术论文10余篇。

四、 代表性研究成果

1.  Wang Meimei, Yang Zhenyu, Song Yang, et al. Proteasomal and autophagy-mediated degradation of mutp53 proteins through mitochondria-targeting aggregation-induced-emission materials[J]. Acta Biomaterialia, 2022, 150: 402-412.

2. Wang Meimei, Ma Hang, Li Zhaoxing, et al. SPG-56 from Sweet potato Zhongshu-1 delayed growth of tumor xenografts in nude mice by modulating gut microbiota[J]. Journal of Functional Foods, 2019, 52: 291-301.

3. Wang Meimei, Ma Hang, Tian Cheng, et al. Bioassay-guided isolation of glycoprotein SPG-56 from sweet potato Zhongshu-1 and its anti-colon cancer activity in vitro and in vivo[J]. Journal of Functional Foods, 2017, 35: 315-324.

4. Tian Cheng, Wang Meimei, Liu Shanshan, et al. A new glycoprotein SPG-8700 isolated from sweet potato with potential anti-cancer activity against colon cancer[J]. Natural product research, 2019, 33(16): 2322-2328.

5. Jing Manman, Li Yafei, Wang Meimei, et al. Photoresponsive PAMAM‐Assembled Nanocarrier Loaded with Autophagy Inhibitor for Synergistic Cancer Therapy[J]. Small, 2021, 17(38): 2102295.

6. Ishimwe Nestor, Wei Pengfei, Wang Meimei, et al. Autophagy impairment through lysosome dysfunction by brucine induces immunogenic cell death (ICD)[J]. The American Journal of Chinese Medicine, 2020, 48(08): 1915-1940.

7. Ma Hang, Yu Yang, Wang Meimei, et al. Correlation between microbes and colorectal cancer: tumor apoptosis is induced by sitosterols through promoting gut microbiota to produce short-chain fatty acids[J]. Apoptosis, 2019, 24(1): 168-183.

8. Li Zhaoxing, Yu Yang, Wang Meimei, et al. Anti-breast cancer activity of SPG-56 from sweet potato in MCF-7 bearing mice in situ through promoting apoptosis and inhibiting metastasis[J]. Scientific reports, 2019, 9(1): 1-12.